Volume Density, Distribution, and Ultrastructure of Secretory and Basolateral Membranes and Mitochondria Predict Parietal Cell Secretory (Dys)function

Figure 6

Lamellar and dense granular bodies were uncommon in WT parietal cell cytoplasm (see Figure 1). Lamellar inclusions were increased in NHE2−/−, AE2−/− and NHE2−/− AE2−/− mice. Lamellar inclusions decreased in the NHE2−/− parietal cells when secretion was inhibited. In GHKA𝛼−/− mice, inclusions were almost always dense and granular. L, lamellar inclusions, G dense granular inclusions; bar: 1 micron for all.

(a)

(b)

(c)

(d)