Pre-mRNA Processing Is Partially Impaired in Satellite Cell Nuclei from Aged Muscles
Figure 1
(a) Satellite cell density (number of satellite cells/1000 of muscle) in the biceps and quadriceps muscles of adult and old rats (mean ± SE). Asterisks show significantly different values ( for both muscles). The inset shows a satellite cell labeled with the anti-N-CAM antibody (green fluorescence); DNA was stained with Hoechst 33258. Bar: 10 m. (b) Percentage of apoptotic satellite cells in the biceps and quadriceps muscles of adult and old rats (mean ± SE). The values were not significantly different ( for biceps and for quadriceps). The inset shows an apoptotic satellite cell (green fluorescence); DNA was stained with Hoechst 33258, note the marginated chromatin. Bar: 10 m.
