Research Article

Optimal Fluxes, Reaction Replaceability, and Response to Enzymopathies in the Human Red Blood Cell

Figure 5

Maps of fluxes in the healthy hRBC (a) and flux rerouting in three full enzymopathies: PK (b), G6PDH (c) and HK (d). The thick arrows are dark grey if the reaction rates diminish with respect to the healthy cell, light grey if they are higher, black if they remains the same. The widths of the arrows are proportional to the mean value of the corresponding distributions.
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(a)
415148.fig.005b
(b)
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(c)
415148.fig.005d
(d)