Cytokine-Induced NK-Like T Cells: From Bench to Bedside

Table 1

Comparison of the three subsets of cells in a CIK culture. NA = not applicable, ND = not done.

Subset	Name	Cytotoxicity			Target class I		Immunophenotype
		versus	versus	versus	Blocked	Enhanced	%CD8	Memory T cell subset	Granzyme
		AML	ALL	K562					content
CD3^−D56^+	NK cells	+	0	++++	Killing ↑	Killing ↓	NA	NA	ND
CD3^+CD56^+	NK-like T cells	+++	0	0	Killing ↓	Killing ↑	higher	CD27^+/−CD28^−CD62L^+ late T effector	higher
CD3^+CD56^−	T cells	+	0	0	Killing ↓	Killing ↑	lower	CD27^+CD28^+CD62L^+early T effector	lower