Review Article

Inflammatory and Autoimmune Reactions in Atherosclerosis and Vaccine Design Informatics

Table 1

B-cell epitope prediction tools. This table, adapted from Table 1 [164] summarizes available websites for B-cell epitope prediction. The prediction mechanisms employed, URLs, or authors’ email addresses are included. Detailed descriptions and references are included in the paper.

NameDescriptionURL

ABCpredBased on sequence using recurrent neural network modulehttp://www.imtech.res.in/raghava/abcpred/
BEPITOPEBased on sequence to predict continuous epitopes[email protected]
BeproBased on structure of the antigen to predict discontinuous B cell epitopeshttp://pepito.proteomics.ics.uci.edu/
CEPBased on structure for the prediction of continuous and discontinuous epitopeshttp://bioinfo.ernet.in/cep.htm
COBEproBased on primary sequence of continuous B cell epitopes. Secondary structure and solvent accessibility information can be incorporated to improve predictionhttp://scratch.proteomics.ics.uci.edu/
DiscoTopeBased on sequence and structure for the prediction of discontinuous epitopeshttp://www.cbs.dtu.dk/services/DiscoTope/
ElliproBased on solvent accessibility and protein flexibilityhttp://tools.immuneepitope.org/tools/ElliPro/iedb_input
EMTBased on Phage-display for the prediction of continuous and discontinuous epitopes[email protected]
EPIMAPBased on Phage-display for the prediction of continuous and discontinuous epitopes[email protected]
EpitopiaBased on either protein 3-D structure or linear sequence using training datahttp://epitopia.tau.ac.il
IEDB B-cell epitope toolsPredict continuous B cell epitope based on amino acids scales and discontinuous epitopes based on 3D structureshttp://tools.immuneepitope.org/main/html/bcell\_tools.html