Review Article
Molecular and Therapeutic Potential and Toxicity of Valproic Acid
Table 1
Ongoing clinical studies implicating valproic acid in monotherapies.
| Dependences |
| Alcohol abuse or dependence | Alcoholism | Cocaine dependence | Marijuana abuse | Substance abuse or dependence | Substance withdrawal syndrome |
| Cancer |
| Autoimmune lymphoproliferative syndrome | Brain and central nervous system tumor | Breast cancer | CLL | HTLV-I associated myelopathy | MDS risk; AML | Nasopharyngeal carcinoma | Prostate cancer | Sarcoma |
| Neurological disorders |
| Alzheimer disease | Amyotrophic lateral sclerosis | Attention deficit hyperactivity disorder | Autism | Bipolar disorder | Borderline personality disorder | Cluster headache | Dementia | Depression | Disruptive behavior | Epilepsy | Mania | Migraine | Mood disorder | Neuralgia | Phosphosensitive epilepsy | Post traumatic stress disorder | Progessive supranuclear palsy | Resistant bipolar depression | Schizophrenia | Spinal muscular atrophy type 1 |
| Others |
| Asthma | Hypersplenism; lymphadenopathy | Hypoalbunemia | Insulin resistance |
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