Table 2: Mean (±SEM) number of TUNEL-positive cells per tissue section for different groups of mice.

Treatment groupsHypothalamus spleen kidney

(1) Normothermic controls (NCs)0
(2) Sham-operated, vehicle-treated heatstroke (SOH) mice 3 4 4 ± 1 0 7
(3) Castrated, vehicle-treated heatstroke (CVH) mice 7 0 ± 1 7
(4) Castrated, testosterone-treated heatstroke (CTH) mice 3 1 2 ± 9 5

* 𝑃 < . 0 5 in comparison to group 1; ** 𝑃 < . 0 5 in comparison to group 2;
*** 𝑃 < . 0 5 in comparison to group 3. Vehicle or testosterone was administered 14 days before whole body heating, and the tissue section was obtained for TUNEL assay 2.5 h post-WBH. Data are means ± SEM of 7 mice per group