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Journal of Biomedicine and Biotechnology
Volume 2010 (2010), Article ID 510682, 10 pages
http://dx.doi.org/10.1155/2010/510682
Review Article

Nanofibers Offer Alternative Ways to the Treatment of Skin Infections

Department of Microbiology, University of Stellenbosch, Matieland, Stellenbosch 7602, South Africa

Received 18 March 2010; Accepted 8 June 2010

Academic Editor: Effie Tsakalidou

Copyright © 2010 T. D. J. Heunis and L. M. T. Dicks. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Injury to the skin causes a breach in the protective layer surrounding the body. Many pathogens are resistant to antibiotics, rendering conventional treatment less effective. This led to the use of alternative antimicrobial compounds, such as silver ions, in skin treatment. In this review nanofibers, and the incorporation of natural antimicrobial compounds in these scaffolds, are discussed as an alternative way to control skin infections. Electrospinning as a technique to prepare nanofibers is discussed. The possibility of using these structures as drug delivery systems is investigated.