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Journal of Biomedicine and Biotechnology
Volume 2010 (2010), Article ID 534501, 7 pages
http://dx.doi.org/10.1155/2010/534501
Research Article

Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice

1Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy
2Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy
3Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy
4Division of Infectious Diseases, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, P.O. Box 1090, New York, NY 10029, USA

Received 14 December 2009; Revised 27 February 2010; Accepted 9 March 2010

Academic Editor: Kim Klonowski

Copyright © 2010 Donatella R. M. Negri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Donatella R. M. Negri, Zuleika Michelini, Silvia Baroncelli, et al., “Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice,” Journal of Biomedicine and Biotechnology, vol. 2010, Article ID 534501, 7 pages, 2010. doi:10.1155/2010/534501