What We Know and Do Not Know about Sex and Cardiac Disease

Figure 2

Schematic representation of VLDL and FFA flux. Women demonstrate higher rates of FFA release as a result of higher lipolytic rates when compared to men. This is consistent with elevated rates of VLDL production and clearance in women. In addition, the molar ratio between hepatic VLDL-TG and VLDL-apoB-100 was greater in women compared to men suggesting that women secrete larger, more TG-rich VLDL particles than men, which may contribute to some of the observed sex dimorphisms.