The Mysterious Unfoldome: Structureless, Underappreciated, Yet Vital Part of Any Given Proteome

Figure 4

Schematic representation of the native/8 M urea 2D electrophoresis for separation of extended IDPs and globular proteins. A continuous line marks the diagonal of the gel to where IDPs run. A dashed line marks the position of globular proteins. A few proteins with a mixture of ordered and disordered regions are also indicated as “Partial IDPs”.