iTRAQ Quantitative Analysis of Multidrug Resistance Mechanisms in Human Gastric Cancer Cells
Figure 5
The effect of MVP siRNA treatment on chemosensitivity in SGC7901/VCR cells. (a) Western blot analysis showed that treatment of SGC7901/VCR cells with MVP siRNA significantly reduced MVP protein levels, whereas MVP protein expressions was not significantly suppressed by control siRNA. (b) MTT assay showed that MVP siRNA transfection could significantly decrease the cell viability of SGC7901/VCR cells incubated with adriamycin and vincristine. The experiment was repeated in triplicate. Points, mean viable cells (% of control) from three experiments; bars, SE. *, differ from control by t-test. Oligofectamine, cells treated with oligofectmine only.
