Substance P Signaling Contributes to Granuloma Formation in Taenia crassiceps Infection, a Murine Model of Cysticercosis

Figure 1

(a) Representative granuloma derived from infected WT, SPP-knockout, and NK1-knockout mice (white bar = 1 mm). (b) Volumes of granulomas derived from Taenia crassiceps infected, wild type (𝑛=2) versus SPP-knockout (𝑛=4) and NK1-knockout mice (𝑛=3). Data presented are mean ± SD; *𝑃<05, size of infected, SPP-knockout derived granulomas versus WT derived granulomas, ^†𝑃<.05, size of infected, NK1-knockout derived granulomas versus WT derived granulomas.

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