Research Article

FSHR Single Nucleotide Polymorphism Frequencies in Proven Fathers and Infertile Men in Southeast Turkey

Table 1

Genotypic frequencies and serum FSH concentrations (mean ± SD) in proven fathers and the two groups of infertile patients.

Proven fathersNonobstructive azoospermicSevere oligozoospermic
Allele combination ( 𝑛 = 2 4 0 ) ( 𝑛 = 1 5 0 ) ( 𝑛 = 1 2 0 )

Genotypic frequency 𝑛 (%)FSH (IU/I)Genotypic frequency 𝑛 (%)FSH (IU/I)Genotypic frequency 𝑛 (%)FSH (IU/I)

At position 29

 AA13 (5.4)3.4 ± 0.48 (5.3)25.5 ± 2.86 (5)11.9 ± 4,8
 AG49 (20.4)3.4 ± 0.326 (17.3)23.6 ± 1.427 (22.5)13.9 ± 6.7
 GG178 (74.2)3.5 ± 0.4116 (77.3)23.4 ± 2.487 (72.5)14.3 ± 5.5

At codon 680

 Asn-Asn154 (64.2)3.4 ± 0.394 (62.7)22.3 ± 1.182 (68.3)11.9 ± 4.5
 Asn/Ser49 (20.4)3.3 ± 0.246 (30.7)22.2 ± 1.213 (10.8)14.1 ± 3.0
 Ser-Ser37 (15.4)3.3 ± 0.410 (6.6)23.0 ± 1.325 (20.8)13.4 ± 3.5