Table 2: Allele combinations considering the FSHR polymorphisms at 29 and codon 680, genotype distribution, and serum FSH levels (mean ± SE) in men with proven fathers and infertile (nonobstructive azoospermic and severe oligozoospermic). *The first three groups (1, 2, and 3) were combined as one group in the Chi-square test.

GroupAllele combination ( 29/680)Proven fathersNonobstructive azoospermicSevere Oligozoospermic
( 𝑛 = 2 4 0 ) ( 𝑛 = 1 5 0 ) ( 𝑛 = 1 2 0 )
Frequency 𝑛 (%)FSH (IU/I)Frequency 𝑛 (%)FSH (IU/I)Frequency 𝑛 (%)FSH (IU/I)

1*A-Asn/A-Asn8 (3.33)3.1 ± 0.45 (3.33)23.1 ± 1.94 (3.33)11.3 ± 5.7
2*A-Asn/A-Ser2 (0.83)2.9 ± 0.43 (2.00)23.5 ± 1.91 (0.83)12.5 ± 6.1
3*A-Ser/A-Ser2 (0.83)3.0 ± 0.51 (0.67)24.0 ± 2.01 (0.83)12.7 ± 6.4
4A-Asn/G-Asn31 (12.92)3.4 ± 0.317 (11.33)22.4 ± 1.221 (17.50)12.3 ± 6.8
5A-Asn/G-ser or G-Asn/A-Ser10 (4.17)3.3 ± 0.38 (5.33)22.8 ± 1.73 (2.50)13.5 ± 7.2
6A-Ser/G-Ser7 (2.92)3.4 ± 0.42 (1.33)23.3 ± 1.36 (5.00)13.6 ± 7.4
7G-Asn/G-Asn117 (48.75)3.5 ± 0.473 (48.67)21.5 ± 1.159 (49.17)12.5 ± 5.5
8G-Asn/G-Ser36 (15.00)3.3 ± 0.434 (22.67)21.7 ± 1.38 (6.67)13.7 ± 6.2
9G-Ser/G-Ser27 (11.25)3.4 ± 0.47 (4.67)22.4 ± 1.317 (14.17)13.8 ± 6.0