Modulation of Muscle Atrophy, Fatigue and MLC Phosphorylation by MuRF1 as Indicated by Hindlimb Suspension Studies on MuRF1-KO Mice
Figure 4
Tetanus Contraction. We stimulated the soleus muscle to a maximum tetanic contraction at a stimulus frequency of 150 Hz. (a) Example of a tetanus of a wt mouse. (b) Mean results of wt and MuRF1-KO mice who had been suspended or unsuspended. There is a significant difference when comparing the absolute peak tetanic force. The data from wt unsuspended mice are significantly different from those of wt suspended mice. However, there is no significant force reduction between the KO unsuspended and the KO suspended mice. (c) Specific tetanic force comparisons did not reveal a significant difference.
