The Role of Genetic Variation Near Interferon-Kappa in  Systemic Lupus Erythematosus

<table>Haplotype diagrams showing LD structure between SNPs near the <i><i>IFNK </i></i> gene in each ancestral background. Generated using Haploview 4.1 software, the plots show pairwise comparisons between each SNP in each ancestral background as <svg height="7.0124998" id="M31" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 6.5 7.0124998" width="6.5" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,7.0125)">
<g transform="translate(72,-66.39)">
<text transform="matrix(1,0,0,-1,-71.95,66.44)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑟</tspan>
</text>
</g>
</g>
</svg>-squared values. Increased dark shading indicates higher <svg height="7.0124998" id="M32" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 6.5 7.0124998" width="6.5" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,7.0125)">
<g transform="translate(72,-66.39)">
<text transform="matrix(1,0,0,-1,-71.95,66.44)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑟</tspan>
</text>
</g>
</g>
</svg>-squared values between the two SNPs. Eur. European ancestry, Af-Am. African-American ancestry.</table>

BioMed Research International

fig1

Figure 1

Figure 1: The Role of Genetic Variation Near Interferon-Kappa in  Systemic Lupus Erythematosus 