Mechanism of Catch Force: Tethering of Thick and Thin Filaments by Twitchin
Figure 10
Dependence of total force and catch force on noncatch force under various conditions in permeabilized ABRM. The data are derived from the same experiments shown in Figure 9. Noncatch force is that remaining after addition of cAMP, while catch force (, solid line) is the change in force resulting from addition of cAMP. Total force (○, dashed line) is the force before cAMP addition. Also shown are the mean SE for catch force remaining 10 minutes () and 20 minutes () after switch from pCa 6 to pCa 8. The lines are least squares quadratic fits to the data. Reproduced from [98] with permission.
, solid line) is the change in force resulting from addition of cAMP. Total force (○, dashed line) is the force before cAMP addition. Also shown are the mean SE for catch force remaining 10 minutes (
) and 20 minutes (
) after switch from pCa 6 to pCa 8. The lines are least squares quadratic fits to the data. Reproduced from [
