Titin-Isoform Dependence of Titin-Actin Interaction and Its Regulation by S100A1/ in Skinned Myocardium
Figure 5
Example experiment addressing effect of calcium and S100A1 on tension in skinned muscle during stretch. (a) Skinned MLV muscle was stretched (0.1 length/sec) in pCa 9.0 (black), pCa 6.8 (red), and pCa 9.0 plus S100A1 solution (blue). Calcium (pCa 6.8) or S100A1 alone did not affect tension during stretch. (b) Skinned MLV muscle was stretched (0.1 length/sec) in pCa 9.0 (black), pCa 6.8 (red squares), and pCa 6.8 plus S100A1 solution (red triangles). Only when calcium (pCa 6.8) and S100A1 are both present is passive tension reduced.
