Titin-Isoform Dependence of Titin-Actin Interaction and Its Regulation by S100A1/Ca²⁺ in Skinned Myocardium

Table 1

Measurement of maximal active tension (pCa 4.5) before and after gelsolin treatment. Percent reduction not different between groups. (SL 2.0 𝜇m; 𝑛 = 6 per group; data are mean ± SE; ^∗∗∗𝑃<.001.

Muscle	Dominant Isoform	Active tension before gelsonlin treatment (mN/mm^2)	Active tension after gelsonlin treatment (mN/mm^2)	Percent tension reduction (%)
MLV	N2B	36.7±0.9	2.25 ± 0.26***	93.8±0.8
BLV	Coexpressing	41.8±1.5	2.24 ± 0.16***	94.6±0.3
BLA	N2BA	33.2±0.5	2.31 ± 0.24***	93.0±0.7