The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity

Table 1

Consequences of decreased IL-2 production in SLE disease.

(i)	Decreased activation-induced cell death (AICD) [3, 4, 35–37].
(ii)	Decreased number and function of Treg cells [38–40].
(iii)	May lead to decreased cytotoxic activity [41, 42].