|Table 2: T. cruzi genes selected by in silico analysis and predicted properties of the encoded hypothetical proteins.|
|L. major and T. brucei gene ID No. of putative orthologs from GeneDB. |
Nonsyntenic predicted orthologs in the TriTrypDB server.
SPP Signal peptide probability predicted by SignalP 3.0.
CSP Maximal cleavage site probability predicted by SignalP 3.0.
TM Number of transmembrane domains (other than peptide signal sequence) predicted by TMHMM 2.0.
GPI Identification of GPI-anchor signal by GPI-SOM.
Conserved domains (and corresponding E-value) from InterPro, PROSITE or Pfam.
Tc00.1047053505789.10 and Tc00.1047053509835.30 are homologous genes presenting 45% identity at the protein level. These genes are members of a multigene family including Tc00.1047053505789.20, Tc00.1047053509441.10, Tc00.1047053510063.30, Tc00.1047053510065.10, and Tc00.1047053504235.9.
Tb927.8.6700, Tb927.8.6710, Tb927.8.6720, and Tb927.8.6730 represent the paralogs/orthologs of Tc00.1047053505789.10, Tc00.1047053505789.20, Tc00.1047053509441.10, Tc00.1047053510063.30, and Tc00.1047053510065.10 in the TriTrypDB server.
Tb11.39.0005 represents the predicted ortholog of Tc00.1047053509835.30 and Tc00.1047053504235.9 in the TriTrypDB server.