- About this Journal
- Abstracting and Indexing
- Aims and Scope
- Annual Issues
- Article Processing Charges
- Articles in Press
- Author Guidelines
- Bibliographic Information
- Citations to this Journal
- Contact Information
- Editorial Board
- Editorial Workflow
- Free eTOC Alerts
- Publication Ethics
- Reviewers Acknowledgment
- Submit a Manuscript
- Subscription Information
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2010 (2010), Article ID 783297, 5 pages
Postnatal BDNF Expression Profiles in Prefrontal Cortex and Hippocampus of a Rat Schizophrenia Model Induced by MK-801 Administration
1Key Laboratory of Mental Health, Institute of Mental Health, Peking University, Beijing 100191, China
2Department of Psychopharmacology, Institute of Mental Health, Peking University, Beijing 100191, China
Received 18 April 2010; Accepted 10 May 2010
Academic Editor: Xudong Huang
Copyright © 2010 Chunmei Guo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- D. R. Weinberger, “On the plausibility of “the neurodevelopmental hypothesis” of schizophrenia,” in Proceedings of the Symposium on a New Understanding: Neurological Basis and Long-Term Outcome of Schizophrenia, at the CINP Congress, Elsevier Science, Washington, DC, USA, 1994.
- A. E. Rehn and S. M. Rees, “Investigating the neurodevelopmental hypothesis of schizophrenia,” Clinical and Experimental Pharmacology and Physiology, vol. 32, no. 9, pp. 687–696, 2005.
- B. D. Pearce, “Schizophrenia and viral infection during neurodevelopment: a focus on mechanisms,” Molecular Psychiatry, vol. 6, no. 6, pp. 634–646, 2001.
- M. Cannon, P. B. Jones, and R. M. Murray, “Obstetric complications and schizophrenia: historical and meta-analytic review,” American Journal of Psychiatry, vol. 159, no. 7, pp. 1080–1092, 2002.
- C. S. Weickert and D. R. Weinberger, “A candidate molecule approach to defining developmental pathology in schizophrenia,” Schizophrenia Bulletin, vol. 24, no. 2, pp. 303–316, 1998.
- P. Ernfors, C. Wetmore, L. Olson, and H. Persson, “Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family,” Neuron, vol. 5, no. 4, pp. 511–526, 1990.
- M. Hofer, S. R. Pagliusi, A. Hohn, J. Leibrock, and Y.-A. Barde, “Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain,” EMBO Journal, vol. 9, no. 8, pp. 2459–2464, 1990.
- E. J. Huang and L. F. Reichardt, “Neurotrophins: roles in neuronal development and function,” Annual Review of Neuroscience, vol. 24, pp. 677–736, 2001.
- G. R. Lewin and Y.-A. Barde, “Physiology of the neurotrophins,” Annual Review of Neuroscience, vol. 19, pp. 289–317, 1996.
- B. Lu, “BDNF and activity-dependent synaptic modulation,” Learning and Memory, vol. 10, no. 2, pp. 86–98, 2003.
- A. K. McAllister, “Subplate neurons: a missing link among neurotrophins, activity, and ocular dominance plasticity?” Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 24, pp. 13600–13602, 1999.
- M.-M. Poo, “Neurotrophins as synaptic modulators,” Nature Reviews Neuroscience, vol. 2, no. 1, pp. 24–32, 2001.
- N. Durany, T. Michel, R. Zöchling et al., “Brain-derived neurotrophic factor and neurotrophin 3 in schizophrenic psychoses,” Schizophrenia Research, vol. 52, no. 1-2, pp. 79–86, 2001.
- G. Shoval and A. Weizman, “The possible role of neurotrophins in the pathogenesis and therapy of schizophrenia,” European Neuropsychopharmacology, vol. 15, no. 3, pp. 319–329, 2005.
- C. S. Weickert, T. M. Hyde, B. K. Lipska, M. M. Herman, D. R. Weinberger, and J. E. Kleinman, “Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia,” Molecular Psychiatry, vol. 8, no. 6, pp. 592–610, 2003.
- L. Wiseman Harris, T. Sharp, J. Gartlon, D. N. C. Jones, and P. J. Harrison, “Long-term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism,” European Journal of Neuroscience, vol. 18, no. 6, pp. 1706–1710, 2003.
- B. Adams and B. Moghaddam, “Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine,” Journal of Neuroscience, vol. 18, no. 14, pp. 5545–5554, 1998.
- R. E. Steinpreis, J. D. Sokolowski, A. Papanikolaou, and J. D. Salamone, “The effects of haloperidol and clozapine on PCP- and amphetamine-induced suppression of social behavior in the rat,” Pharmacology Biochemistry and Behavior, vol. 47, no. 3, pp. 579–585, 1994.
- M. E. Wolf, “The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants,” Progress in Neurobiology, vol. 54, no. 6, pp. 679–720, 1998.
- Y.-A. Su, T.-M. Si, D.-F. Zhou et al., “Risperidone attenuates MK-801-induced hyperlocomotion in mice via the blockade of serotonin 5-HT2A/2C receptors,” European Journal of Pharmacology, vol. 564, no. 1–3, pp. 123–130, 2007.
- L. P. Spear, “The adolescent brain and age-related behavioral manifestations,” Neuroscience and Biobehavioral Reviews, vol. 24, no. 4, pp. 417–463, 2000.
- M. J. Webster, C. S. Weickert, M. M. Herman, and J. E. Kleinman, “BDNF mRNA expression during postnatal development, maturation and aging of the human prefrontal cortex,” Developmental Brain Research, vol. 139, no. 2, pp. 139–150, 2002.
- A. Danielyan and H. A. Nasrallah, “Neurological disorders in schizophrenia,” Psychiatric Clinics of North America, vol. 32, no. 4, pp. 719–757, 2009.
- J. van Os and S. Kapur, “Schizophrenia,” The Lancet, vol. 374, no. 9690, pp. 635–645, 2009.
- L. M. Monteggia, B. Luikart, M. Barrot et al., “Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors,” Biological Psychiatry, vol. 61, no. 2, pp. 187–197, 2007.
- C. Wang, J. McInnis, M. Ross-Sanchez, P. Shinnick-Gallagher, J. L. Wiley, and K. M. Johnson, “Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia,” Neuroscience, vol. 107, no. 4, pp. 535–550, 2001.
- M. Takahashi, O. Shirakawa, K. Toyooka et al., “Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients,” Molecular Psychiatry, vol. 5, no. 3, pp. 293–300, 2000.
- H. Kang and E. M. Schuman, “Long-lasting neuratrophin-induced enhancement of synaptic transmission in the adult hippocampus,” Science, vol. 267, no. 5204, pp. 1658–1662, 1995.
- M. Takahashi, A. Kakita, T. Futamura et al., “Sustained brain-derived neurotrophic factor up-regulation and sensorimotor gating abnormality induced by postnatal exposure to phencyclidine: comparison with adult treatment,” Journal of Neurochemistry, vol. 99, no. 3, pp. 770–780, 2006.
- Y. Xia, C. Z. Wang, J. Liu, N. C. Anastasio, and K. M. Johnson, “Brain-derived neurotrophic factor prevents phencyclidine-induced apoptosis in developing brain by parallel activation of both the ERK and PI-3K/Akt pathways,” Neuropharmacology, vol. 58, no. 2, pp. 330–336, 2009.
- M. C. Jockers-Scherübl, H. Danker-Hopfe, R. Mahlberg et al., “Brain-derived neurotrophic factor serum concentrations are increased in drug-naïve schizophrenic patients with chronic cannabis abuse and multiple substance abuse,” Neuroscience Letters, vol. 371, no. 1, pp. 79–83, 2004.
- S. Pirildar, A. S. Gönül, F. Taneli, and F. Akdeniz, “Low serum levels of brain-derived neurotrophic factor in patients with schizophrenia do not elevate after antipsychotic treatment,” Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 28, no. 4, pp. 709–713, 2004.
- T. B. Franklin and T. S. Perrot-Sinal, “Sex and ovarian steroids modulate brain-derived neurotrophic factor (BDNF) protein levels in rat hippocampus under stressful and non-stressful conditions,” Psychoneuroendocrinology, vol. 31, no. 1, pp. 38–48, 2006.
- J. Wong, M. J. Webster, H. Cassano, and C. S. Weickert, “Changes in alternative brain-derived neurotrophic factor transcript expression in the developing human prefrontal cortex,” European Journal of Neuroscience, vol. 29, no. 7, pp. 1311–1322, 2009.