Gene Expression Profiling of Placentas Affected by Pre-Eclampsia

Figure 2

The expression patterns of the sequences as determined by real-time PCR. White bars represent pre-eclampsia cases; grey bars represent controls. Each bar represents the mean (+SEM) relative expression of the individual samples in the experiment. 𝑃-values for comparisons between cases and controls were: Fibulin (.619; FC 1.46), leptin (.012; FC 3.41), inhibin (.500; FC 1.13), tyr 3-monooxygenase/tryp 5-monooxygenase activation protein 𝜀 (𝑃=.166; FC−1.27); Mann-Whitney test. (Pre-eclampsia cases: 𝑛=9, controls: 𝑛=12; one control placenta was found to have a cDNA yield which was significantly lower than the other samples and it was therefore excluded from the subsequent analyses.)

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