Functional Differences between the N-Terminal Domains of Mouse and Human Myosin Binding Protein-C
Figure 1
Schematic of full-length cMyBP-C, domain boundaries, and recombinant chimeric mouse and human C0C1 proteins. (a) Schematic of full-length cMyBP-C. The Pro-Ala rich region is denoted by a box between the C0 and C1 domains. (b) Amino acid sequence alignment of mouse and human C0, P/A, and C1 domains. Arrows indicate domain boundaries. Asterisks denote identical residues. (c) Schematic of recombinant chimeric proteins used in this study. Squares represent human domains; circles represent mouse domains.
