Immune Modulation by <i>Schistosoma mansoni</i> Antigens in NOD Mice: Effects on Both Innate and Adaptive Immune Systems

<table>The cellular immune response to <i>S. mansoni</i>  egg antigens in NOD mic: alternative activation of M<svg height="10.475" id="M103" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 12.05 10.475" width="12.05" xmlns="http://www.w3.org/2000/svg">
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</svg>s), maintenance of dendritic cells (DCs) in an immature phenotype, IL-4 release from basophils (B<svg height="10.475" id="M105" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 12.05 10.475" width="12.05" xmlns="http://www.w3.org/2000/svg">
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</svg>s), expansion of classical natural killer T cells (NKT), expansion of T helper 2 (Th2) responses, expansion and activation of T regulatory cells (Tregs), as well as induction of IL-10 production in Th1 cells (Th1) and B cells (B).</table>

BioMed Research International

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Figure 7

Figure 7: Immune Modulation by <i>Schistosoma mansoni</i> Antigens in NOD Mice: Effects on Both Innate and Adaptive Immune Systems 

BioMed Research International

Immune Modulation by Schistosoma mansoni Antigens in NOD Mice: Effects on Both Innate and Adaptive Immune Systems

Figure 7