Promoter Variant of <i>PIK3C3</i> Is Associated with Autoimmunity against Ro and Sm Epitopes in African-American Lupus Patients

<table>Distribution of the number of different autoantibody specificities in African-American SLE patients stratified by rs3813065 genotype. no. of specificities = the sum of the number of positive test results for anti-Ro, anti-La, anti-Sm, anti-RNP, and anti-dsDNA for a given subject (thus every subject is assigned a number 0 through 5). The horizontal line in the middle of the box indicates the median, boundaries of the boxes indicate the interquartile range, and the error bars show the 10th and 90th percentile, respectively. The <svg height="10.325" id="M58" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 11.75 10.325" width="11.75" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.325)">
<g transform="translate(72,-63.74)">
<text transform="matrix(1,0,0,-1,-71.95,63.79)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
</text>
</g>
</g>
</svg> value for the Kruskall-Wallis test is shown.</table>

BioMed Research International

fig2

Figure 2

Figure 2: Promoter Variant of <i>PIK3C3</i> Is Associated with Autoimmunity against Ro and Sm Epitopes in African-American Lupus Patients 

BioMed Research International

Promoter Variant of PIK3C3 Is Associated with Autoimmunity against Ro and Sm Epitopes in African-American Lupus Patients

Figure 2