Expressions of Neuregulin 1 and ErbB4 in Prefrontal Cortex and Hippocampus of a Rat Schizophrenia Model Induced by Chronic MK-801 Administration
Figure 1
Expression of NRG1 and ErbB4 proteins in the rat prefrontal cortex. (a) Representative Western blots of NRG1 protein isoforms. (b) Quantitative analysis of NRG1 immunoblots. (c) Representative Western blots of ErbB4 proteins isoforms. (d) Quantitative analysis of ErbB4 immunoblots. The data were normalized by taking the value of vehicle group as 100% and expressed as means S.E.M. ( = 5). . (e) Representative section of ErbB4 immunohistochemistry in the PrL region of prefrontal cortex from vehicle group. (f) Representative section of ErbB4 immunohistochemistry in the PrL region of prefrontal cortex from MK-801-treated group. (g) Representative section of ErbB4 immunohistochemistry in the Cg1 and M2 region of prefrontal cortex from vehicle group. (h) Representative section of ErbB4 immunohistochemistry in the Cg1 and M2 region of prefrontal cortex from MK-801-treated group. Arrows indicate ErbB4-expressing neurons in the prefrontal cortex. Scale bar for (e)–(h): 50 m.
