Expressions of Neuregulin 1 and ErbB4 in Prefrontal Cortex and Hippocampus of a Rat Schizophrenia Model Induced by Chronic MK-801 Administration
Figure 2
Expression of NRG1 and ErbB4 proteins in the rat hippocampus. (a) Representative Western blots of NRG1 protein isoforms. (b) Quantitative analysis of NRG1 immunoblots. (c) Representative Western blots of ErbB4 protein isoforms. (d) Quantitative analysis of ErbB4 immunoblots. The data were normalized by taking the value of vehicle group as 100% and expressed as means S.E.M. ( = 5). . (e) Representative section of NRG1 immunohistochemistry in the hippocampal CA1 region from vehicle group. (f) Representative section of NRG1 immunohistochemistry in the hippocampal CA1 region from MK-801-treated group. (g) Representative section of NRG1 immunohistochemistry in the hippocampal CA3 region from vehicle group. (h) Representative section of NRG1 immunohistochemistry in the hippocampal CA3 region from MK-801-treated group. (i) Representative section of NRG1 immunohistochemistry in the hippocampal DG region from vehicle group. (j) Representative section of NRG1 immunohistochemistry in the hippocampal DG region from MK-801-treated group. Arrows indicate NRG1-expressing neurons in the hippocampus. Scale bar for (e)–(j): 50 m.
