Research Article

Mexican Trypanosoma cruzi (TCI) Strains with Different Degrees of Virulence Induce Diverse Humoral and Cellular Immune Responses in a Murine Experimental Infection Model

Figure 5

Serum cytokine concentration in mice infected with T. cruzi I strains. Groups of nine mice were inoculated with 1 × 1 0 4 BT Qro () or Ninoa BT (). Serum was obtained from ocular plexus each 3rd day and pooled. Cytokines were measured by ELISA and presented as average of two experiments with standard deviation. (a) IL-12 p40, (b) IFNγ, (c) IL-10, and (d) IL-4. Statistical differences between mice infected with either strain are indicated ( 𝑃 < . 0 5 ) .
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(a)
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(b)
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(c)
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(d)