Mexican Trypanosoma cruzi (TCI) Strains with Different Degrees of Virulence Induce Diverse Humoral and Cellular Immune Responses in a Murine Experimental Infection Model

Table 1

Immunoglobulin isotype and kinetics of antigen recognized in mice infected with T. cruzi I strains.

Strain

Isotype

Antigens recognized (kDa)

Days post-infection

20

25

30

35

40

50

60

70

80

90

100

150

Ninoa

IgG1

45–50

X

X

X

X

X

X

X

X

X

70

X

X

X

X

X

X

X

X

X

100

X

X

X

X

X

IgG2a

45–50

X

X

X

X

X

X

X

X

X

X

X

70

X

X

X

X

X

X

X

X

X

X

100

X

X

X

X

X

X

IgG2b

45–50

X

X

X

X

X

X

X

X

X

70

X

X

X

X

X

X

X

X

100

X

X

IgG3

45–50

X

X

X

X

X

X

X

X

70

X

X

X

X

X

X

X

X

IgM

30

X

X

X

X

X

X

X

X

X

X

X

X

45–50

X

X

X

X

X

X

X

X

X

X

X

70

X

X

X

X

X

X

X

X

X

X

X

IgA

45–50

X

X

X

X

X

X

X

X

70

X

X

X

X

X

X

X

Qro

IgG2a

70

X

X

IgM

40

X

X

X

X

X

35

X

X

X

X

X

Isotype of IgG and molecular weight of antigens recognized during infection course (X) are showed in days post-infection.