Mexican Trypanosoma cruzi (TCI) Strains with Different Degrees of Virulence Induce Diverse Humoral and Cellular Immune Responses in a Murine Experimental Infection Model

Table 2

Percentage of CD4+ and CD8+ lymphocytes in mice infected with T. cruzi I strains.

Strain (infection phase)	Parasites	CD4+	CD8+
Ninoa (acute)	PBS	28.8 ± 1	11.8 ± 0.1
	1×10^4	15.1 ± 2.6*	11.8 ± 2.6
	1×10^5	18 ± 2.5*	16.3 ± 1.9
Ninoa (chronic)	PBS	25.8 ± 8	9.9 ± 4.1
	1×10^4	30.3 ± 11.6	23.2 ± 7.8*
	1×10^5	25.3 ± 7.4	18 ± 8.7*
Qro (acute)	PBS	24 ± 3.3	10.5 ± 4.6
	1×10^4	17 ± 3.3*	11.7 ± 4.3
	1×10^5	14 ± 2.5*	10 ± 6

Mean ± standard deviation of three independent assays. Statistical differences between parasited and control mice are indicated (^∗𝑃<.05). Control mice were inoculated with phosphate buffer saline (PBS).