Figure 1: fdOV administration is able to trigger DTH. Mice were sensitized by one injection of 50 g of cytotoxic OV (SIINFEKL) peptide and 140 g T helper HBV (TPPAYRPPNAPIL) peptide from hepatitis B virus core antigen, emulsified with incomplete Freund’s adjuvant. Ten days after sensitization, DTH was performed by injecting into the right footpad fdOV, fdwt, the synthetic OV peptide (pepOVA), or soluble ovalbumin. 10–48 hours later the area of swelling was measured using a caliper. (a) Curve response of all mice analyzed. (b) Values at 30 hours of mean thickness SD of the different mice groups challenged with the antigens indicated in the abscissa. The -values were calculated by comparing each group with the fdOV challenged group.