Mass Spectrometric Analysis of Multiple Pertussis Toxins and Toxoids

Table 5

Comparative pertussis toxin and toxoid subunit quantitative analysis.

Source	S1	S2	S3	S4	S5	Total (all subunits)
Toxin A	0.38	0.19	0.13	0.02	0.09	0.81
Toxin B	1.48	2.04	1.35	0.37	0.57	5.81
Toxoid C	1.88	0.34	0.32	ND	ND	2.54
Toxoid D	2.91	0.40	0.21	ND	0.06	3.54

-Measured as relative abundance (f mol/𝜇L)
-ND: not detected
-Approach: Electrospray Ionization Mass Spectrometry
-Instrument: Q-Tof Premier only