Nanoparticles Radionuclides Imaging or Radiotherapeutics Applications Reference Liposomes
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Gamma imaging Multitude diagnostics of tumor, infection, Inflammation, and lymphoscintigraphy [28 , 29 , 60 –62 ] Liposomes 111 InGamma/SPECT imaging Clinical biodistribution, PK and imaging studies of breast, head and neck, glioma and lung cancer patients [53 , 62 ] Liposomes 18 FPET imaging Liposomal tracking in vivo with 18 F-limposome-PET imaging [66 –68 ] Liposomes 111 In, 177 LuGamma/SPECT imaging Gamma imaging of tumor targeting for C26 and HT29/luc animal models [70 , 71 ] Liposomes 64 CuPET imaging Passive targeted delivery and imaging with bioconjugated 64 Cu-BAT- PEG-liposome [69 ] Liposomes 131 I, 90 Y, 188 Re, 67 CuRadiotherapeutics An analytical dosimetry study for the use of radionuclide-liposome conjugates in internal radiotherapy [74 ] Liposomes 186 ReRadiotherapeutics Intraoperative 186 Re-liposome radionuclide therapy in a head and neck squanous cell carcinoma xenograft positive surgical margin model [78 ] Liposomes 111 In, 188 ReRadiotherapeutics Imaging, biodistribution, pharmacokinetics, and therapeutic efficacy studies of 111 In/188 Re-liposome on C26 and HT-29 tumor-bearing animal models [70 , 72 , 80 , 81 ] Liposomess 225 AcRadiotherapeutics Targeted
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-particles emitters of 225 Ac-generators encapsulated in liposomes as therapeutic agents for micrometastases cancer [82 –84 ] Liposomes 10 BRadiotherapeutics 10 B-liposomes nanotargeted therapeutics for boron neutron capture therapy (BNCT)[85 , 86 ] Liposomes 111 In, 188 ReRadiochemo-therapeutics Imaging, biodistribution, pharmacokinetics, therapeutic efficacy, and dosimetry studies of 111 In/188 Re-VNB/DXR-liposome on C26 and HT-29 tumor/ascites-bearing animal models [71 , 73 , 81 , 90 –93 ]
