Nanotargeted Radionuclides for Cancer Nuclear Imaging and Internal Radiotherapy
Table 5
Selected actively nanotargeted tumor nuclear imaging and radiotherapeutic applications.
Nanoparticles
Radionuclides
Imaging or Radiotherapeutics
Applications
Reference
Immunoliposome
111In
Gamma imaging and therapeutics
111In-liposome-2C5(mAb) nucleosome-specific monoclonal 2C5 targeting delivery vehicles for tumor visualization of murine lewis lung carcinoma and human HT-29 tumors
111In labeled 3-component streptavidin (111In-MORF/tat/trastuzmab) nanoparticles for auger electron induced antisense-mediated cytoxicity of tumor cells
Targeted antiangiogenesis of -integrin or VEGFR2 anti-FLK-1 therapy with nanotargeted therapeutics of 90Y-DTPA-liposome-IA(integrin antagonist) or 90Y-DTPA-liposome-mAb