Table 1: Genotypic distribution and allelic frequencies of −1722 CTLA-4 polymorphisms in Chinese SLE patients and healthy controls.

Promoter −1722SLE
Controls
valueOR (95% CI)

Genotype frequency
TT42 (28.4%)29 (17.1%)5.8460.0161.926 (1.127–3.293)
TC87 (58.8%)80 (47.1%)4.3620.0371.605 (1.028–2.503)
CC19 (12.8%)61 (35.8%)22.315 0.263 (0.148–0.468)
Allele frequency
T171 (57.8%)138 (40.6%)18.701 2.002 (1.459–2.747)
C125 (42.2%)202 (59.4%)
Phenotype
T129 (87.2%)109 (64.1%)6.1820.0131.574 (1.100–2.253)
C106 (71.6%)141 (82.9%)

Abbreviations: CTLA-4 = cytotoxic T-lymphocyte antigen 4; SLE =systemic lupus erythematosus; OR = odds ratios; 95% CI = 95% confidence interval.