Table 2: Genotypic distribution and allelic frequencies of −1661 CTLA-4 polymorphisms in Chinese SLE patients and healthy controls.

Promoter −1661SLE
Controls
-valueOR (95% CI)

Genotype frequency
AA59 (39.9%)63 (37.1%)0.2630.6081.126 (0.716–1.771)
AG67 (45.2%)76 (44.7%)0.0100.9201.132 (0.730–1.755)
GG22 (14.9%)31 (18.2%)0.6470.4210.783 (0.431–1.423)
Allele frequency
A185 (62.5%)202 (59.4%) 0.6330.4261.139 (0.827–1.568)
G111 (37.5%)138 (40.6%)
Phenotype
A126 (85.1%)139 (81.8%)0.2070.6491.090 (0.752–1.578)
G89 (60.1%)107 (62.9%)

Abbreviations: CTLA-4 = cytotoxic T-lymphocyte antigen 4; SLE = systemic lupus erythematosus; OR = odds ratios; 95% CI = 95% confidence interval.