Table 2: Relative potency determination of IFN variants compared with the reference standards.

LL of estimated potency*Estimated potency* UL of estimated potency*LL of relative potency (%)Relative  potency (%)#UL of relative potency  (%)

Oxidized2655720209369002646830061.3077.5098.00
Deaminated22397100283276003583070083.00104.90132.70
Aggregated3379358875991150.100.2200.4

*:Actual reading of luciferase activity;
#:Relative potency compared with the reference standards as determined by statistical analyses (bold face). The values in bold face refer to the relative potency of the samples with respect to the reference standards (EDQM IFN-α 2a). LL stands for lower limits of the 95% interval while UL denotes upper limits of the 95% interval.