Research Article

Intermittent Chemotherapy and Erlotinib for Nonsmokers or Light Smokers with Advanced Adenocarcinoma of the Lung: A Phase II Clinical Trial

Table 2

Response to treatment, time to progression, and survival in relation to EGFR mutations.

EGFR mutations
PositiveNegativeUnknownAll

Response to treatmentCR415
PR4239
SD628
Progression22
Time to progression (months)Median (95% CI)21.5 (14.8–27.2)5.0 (0.9–9.1)5.0 (3.9–4.1)13.4 (5.4–20.6)
Survival (months)Median (95% CI)24.27.0 (0.1–13.9)11.023.0 (10.9–35.2)