Research Article

Investigation of Hepatoprotective Activity of Induced Pluripotent Stem Cells in the Mouse Model of Liver Injury

Table 2

Effect of intravenous transplantation of PBS or iPSCs clone 1 Re7 from our lab on hepatic biochemical parameters in TAA-treated recipients.

Alanine aminotransferase (ALT; IU/L)Aspartate aminotransferase (AST; IU/L)Total bilirubin (TBIL; mg/dL)

Recipient after 24 hours
 PBS20702 ± 16316956 ± 5222.0 ± 0.3
 iPSCs5175 ± 509*1932 ± 290*1.3 ± 0.2*

Recipient after 72 hours
 PBS1721 ± 4971116 ± 2861.0 ± 0.2
 iPSCs312 ± 62*248 ± 76*0.5 ± 0.1*

Results were expressed as mean ± SD. * versus PBS.