Investigation of Hepatoprotective Activity of Induced Pluripotent Stem Cells in the Mouse Model of Liver Injury

Table 3

Effect of intravenous transplantation of PBS or iPSCs clone 2 from Dr. Shinya Yamanaka on hepatic biochemical parameters in TAA-treated recipients.

	Alanine aminotransferase (ALT; IU/L)	Aspartate aminotransferase (AST; IU/L)	Total bilirubin (TBIL; mg/dL)
Recipient after 24 hours
PBS	17768.2 ± 786.9	6875.2 ± 929.1	3.87 ± 0.45
iPSCs	3157.4 ± 336.8*	1512.9 ± 257.1*	1.53 ± 0.46*
Recipient after 72 hours
PBS	1553.4 ± 67.1	984.7 ± 26.2	1.53 ± 0.18
iPSCs	217.7 ± 7*	175.1 ± 8.4*	0.92 ± 0.13*

Results were expressed as mean ± SD. *𝑃<0.05 versus PBS.