Equal Force Recovery in Dysferlin-Deficient and Wild-Type Muscles Following Saponin Exposure

Table 2

Tetanic forces (kN/m²) of WT and dysferlin-null soleus muscles at room temperature before and after saponin exposure.

	Initial	10 min	20 min	30 min	40 min	50 min	60 min
WT, N = 5	166.5 ± 6.7	130.8 ± 4.1	139.8 ± 3.6; ^(a)𝑃 = 0.002	137.7 ± 3.1; P = 0.32	135.0 ± 2.8; P = 0.04	133.4 ± 2.9; P = 0.75	132.2 ± 3.9; P = 0.94
KO, N = 7	171.0 ± 11.9	138.3 ± 8.4	145.6 ± 8.3; P = 0.003	142.6 ± 7.8; P = 0.15	139.7 ± 7.6; P = 0.13	138.5 ± 7.6; P = 0.34	136.9 ± 7.8; P = 0.42
^(b)𝑃	0.77	0.49	0.59	0.62	0.63	0.60	0.64

Note: (a) the P values under the force data are the paired t-test of the forces at the specific time point compared to that measured at the prior time point (e.g., WT force at 20 min compared to that at 10 min); (b) the P values in the last row are the unpaired t-test of forces between WT and dysferlin-null groups at each time point.