Possible Involvement of Tight Junctions, Extracellular Matrix and Nuclear Receptors in Epithelial Differentiation

Table 1

Nuclear receptors induce the expression of claudins.

Nuclear receptors	Induced claudin expression	Cells	References
Retinoic acid receptor	Cldn1, Cldn4	Human nasal epithelium	[83]
	Cldn3	Human urothelium	[84]
	Cldn6, Cldn7	Mouse F9 stem cell	[81]
	Cldn23	Mouse epidermis	[82]
Hepatocyte nuclear factor 4𝛼 (HNF4𝛼)	Cldn6, Cldn7	Mouse F9 stem cell	[85, 86]
	Cldn1	Mouse hepatocyte	[87]
Androgen receptor	Cldn3	Mouse Seltoli cell	[88]
Progesterone receptor	Cldn3, Cldn4	Mouse amniotic epithelium	[89]
Corticoid receptor	Cldn3, Cldn4	Gill epithelium	[90]
Vitamin D receptor	Cldn2, Cldn12	Mouse intestinal Caco-2 cell	[91]