Development of ⁶⁸Ga-Glycopeptide as an Imaging Probe for Tumor Angiogenesis

Table 1

Biodistribution of ⁶⁸Ga-GP in breast tumor-bearing Rats. % of injected dose per gram of tissue weight (𝑛=3/time, interval, iv)*.

	30 min	60 min	120 min
Blood	2.61 ± 0.18	1.81 ± 0.05	1.37 ± 0.05
Heart	0.59 ± 0.06	0.43 ± 0.02	0.32 ± 0.02
Lung	2.34 ± 0.45	2.58 ± 0.16	1.38 ± 0.06
Thyroid	1.10 ± 0.11	1.40 ± 0.87	0.59 ± 0.06
Pancreas	0.38 ± 0.03	0.34 ± 0.04	0.28 ± 0.02
Liver	3.81 ± 0.32	4.83 ± 0.54	4.94 ± 0.38
Spleen	2.13 ± 0.07	2.65 ± 0.14	2.97 ± 0.11
Kidney	1.35 ± 0.02	1.36 ± 0.01	1.41 ± 0.11
Stomach	0.58 ± 0.04	0.65 ± 0.07	0.74 ± 0.18
Intestine	0.54 ± 0.12	0.53 ± 0.07	0.78 ± 0.22
Uterus	0.70 ± 0.02	0.65 ± 0.05	0.57 ± 0.03
Tumor	0.68 ± 0.12	0.89 ± 0.10	1.18 ± 0.09
Muscle	0.12 ± 0.02	0.12 ± 0.00	0.10 ± 0.02
Bone	0.45 ± 0.12	0.46 ± 0.09	0.59 ± 0.03
Brain	0.08 ± 0.01	0.07 ± 0.01	0.07 ± 0.01
Tumor/blood	0.26 ± 0.03	0.49 ± 0.07	0.86 ± 0.09
Tumor/muscle	6.12 ± 1.87	7.20 ± 0.83	13.26 ± 4.41

*Value shown represent the mean ± standard deviation of data from 3 animals at (Count at 460–560 keV window).