|Table 2: Genetic studies investigating the association between several SNPs and both lupus nephritis and specific auto-antibodies in different ethnic populations.|
*Severe nephritis (ESRD or severe progressing renal disease in renal biopsy), .**Statistical significance found only in the case-control arm of the study, whereas, in the case-only arm of the study, results both for nephritis and anti-dsDNA reached no statistical significance.|
***While a statistically significant association with lupus nephritis was detected, no association was found with any specific clinical finding or histological type of nephritis.
†These 2 SNPs of the IRF7/KIAA1542 gene were not associated with SLE but only with specific SLE subphenotypes such as nephritis and anti-SSB.
NS: not statistically significant association. NM: not measured.
The rest of the abbreviations used are explained in the text.