BioMed Research International / 2011 / Article / Tab 2 / Research Article
Glucose Tolerance and Left Ventricular Pressure-Volume Relationships in Frequently Used Mouse Strains Table 2 Pressure-conductance analysis in 4 mice background strains. All data are expressed as mean ± standard deviation. Values marked with
ψ are
versus
∆ and values marked with * are
versus all others.
Heart rate (bpm) 623 ± 71* 569 ± 43 545 ± 40 566 ± 35 Ves (uL) 10.9 ± 5.1ψ 16.5 ± 6.2∆ 9.0 ± 3.1ψ 18.0 ± 4.6∆ Ved (uL) 30.7 ± 9.1 31.8 ± 7.2ψ 25.8 ± 7.1∆ 30.0 ± 9.9 Pes (mmHg) 69.5 ± 9.9 76.8 ± 8.2 71.9 ± 8.0 84.2 ± 13.6* Ped (mmHg) 1.2 ± 1.7 1.9 ± 2.0 1.2 ± 1.2 2.9 ± 2.9
(mmHg)90 ± 5ψ 84 ± 6∆ 88 ± 7 89 ± 11 EF (%) 70.4 ± 11.2∆ 55.9 ± 13.4ψ 71.8 ± 9.2∆ 47.8 ± 5.7ψ Cardiac output (uL/min) 14038 ± 4530* 10405 ± 2683 10438 ± 3251 8466 ± 3013
(mmHg/s)11746 ± 2105* 7162 ± 1563 9420 ± 2268 7760 ± 1581
(mmHg/s)−7738 ± 2098 −7948 ± 1242 −8204 ± 1458 −8547 ± 1464 Tau 4.1 ± 0.7ψ 5.2 ± 0.9∆ 4.5 ± 0.7ψ 5.2 ± 0.8∆ Arterial elastance (Ea) (mmHg/μ L) 3.4 ± 1.2 4.4 ± 1.2 4.1 ± 1.1 6.2 ± 1.9* Ees 9.5 ± 5.0 6.1 ± 2.1 8.4 ± 3.8 8.2 ± 2.9 EDPVR (mmHg/μ L) 0.265 ± 0.082 0.218 ± 0.074 0.316 ± 0.079 0.415 ± 0.159* Preload recruitable stroke work (PRSW) (mmHg) 92 ± 22 88 ± 21 94 ± 25 82 ± 23 Efficiency (SW/PVA) 0.78 ± 0.054 0.70 ± 0.08 0.70 ± 0.13 0.60 ± 0.11*