Robust Design of Biological Circuits: Evolutionary Systems Biology Approach
Figure 9
Simulation of biological repressilator: (a) TetR; (b) CI; (c) LacI. In contrast to the above design case, the design parameters are specified aside the best fit parameter , for example, with , , , , , and . In this design case, the mean errors are 0.91, 1.36, and 1.18 with standard deviations of 0.29, 0.35, and 0.27 for TetR, CI, and LacI, respectively.