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Journal of Biomedicine and Biotechnology
Volume 2011 (2011), Article ID 310791, 8 pages
http://dx.doi.org/10.1155/2011/310791
Research Article

Titin-Actin Interaction: PEVK-Actin-Based Viscosity in a Large Animal

1Molecular Cardiovascular Research Program, Sarver Heart Center, Department of Physiology, University of Arizona, Tucson, AZ 85724, USA
2Department of Integrative Pathophysiology, Universitätsmedizin Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany

Received 23 July 2011; Accepted 1 September 2011

Academic Editor: Guy Benian

Copyright © 2011 Charles S. Chung et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Tamás Huber, László Grama, Csaba Hetényi, Gusztáv Schay, Lívia Fülöp, Botond Penke, and Miklós S.Z. Kellermayer, “Conformational dynamics of titin PEVK explored with FRET spectroscopy,” Biophysical Journal, vol. 103, no. 7, pp. 1480–1489, 2012. View at Publisher · View at Google Scholar
  • I. M. Vikhlyantsev, A. D. Okuneva, U. V. Shumilina, N. N. Salmov, A. G. Bobylev, N. V. Molochkov, and Z. A. Podlubnaya, “Method for isolation of intact titin (connectin) molecules from mammalian cardiac muscle,” Biochemistry (Moscow), vol. 78, no. 5, pp. 455–462, 2013. View at Publisher · View at Google Scholar
  • Brian R. Anderson, Julius Bogomolovas, Siegfried Labeit, and Henk Granzier, “Single molecule force spectroscopy on titin implicates immunoglobulin domain stability as a cardiac disease mechanism,” Journal of Biological Chemistry, vol. 288, no. 8, pp. 5303–5315, 2013. View at Publisher · View at Google Scholar
  • Charles S. Chung, and Kenneth S. Campbell, “Temperature and transmural region influence functional measurements in unloaded left ventricular cardiomyocytes,” Physiological Reports, vol. 1, no. 6, 2013. View at Publisher · View at Google Scholar
  • Nima Milani-Nejad, and Paul M.L. Janssen, “Small and Large Animal Models in Cardiac Contraction Research: Advantages and Disadvantages,” Pharmacology & Therapeutics, 2013. View at Publisher · View at Google Scholar
  • Carlos G. Hidalgo, Charles S. Chung, Chandra Saripalli, Mei Methawasin, Kirk R. Hutchinson, George Tsaprailis, Siegfried Labeit, Alicia Mattiazzi, and Henk L. Granzier, “The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements,” Journal of Molecular and Cellular Cardiology, vol. 54, pp. 90–97, 2013. View at Publisher · View at Google Scholar
  • I. M. Vikhlyantsev, and Z. A. Podlubnaya, “New titin (connectin) isoforms and their functional role in striated muscles of mammals: Facts and suppositions,” Biochemistry (Moscow), vol. 77, no. 13, pp. 1515–1535, 2013. View at Publisher · View at Google Scholar
  • Walter Herzog, “Mechanisms of enhanced force production in lengthening (eccentric) muscle contractions,” Journal of Applied Physiology, vol. 116, no. 11, pp. 1407–1417, 2014. View at Publisher · View at Google Scholar
  • Charles S. Chung, Mihail I. Mitov, Leigh Ann Callahan, and Kenneth S. Campbell, “Increased myocardial short-range forces in a rodent model of diabetes reflect elevated content of beta myosin heavy chain,” Archives of Biochemistry and Biophysics, vol. 552, pp. 92–99, 2014. View at Publisher · View at Google Scholar