Using Bacterial Artificial Chromosomes in Leukemia Research: The Experience at the University Cytogenetics Laboratory in Brest, France
Figure 1
Identification of breakpoints involved in a newly recognized recurrent translocation, t(10;17)(p15;q21). (a) Representation of the breakpoint (dotted line) on the short arm of chromosome 10 for both patients by FISH with BACs. Applied BAC clones are bordered; candidate genes are surrounded. (b) Representation of the breakpoint (dotted lines) on the long arm of chromosome 17 for both patients by FISH with BACs. Applied BAC clones are bordered; candidate genes are surrounded.