Review Article

Using Bacterial Artificial Chromosomes in Leukemia Research: The Experience at the University Cytogenetics Laboratory in Brest, France

Figure 1

Identification of breakpoints involved in a newly recognized recurrent translocation, t(10;17)(p15;q21). (a) Representation of the breakpoint (dotted line) on the short arm of chromosome 10 for both patients by FISH with BACs. Applied BAC clones are bordered; candidate genes are surrounded. (b) Representation of the breakpoint (dotted lines) on the long arm of chromosome 17 for both patients by FISH with BACs. Applied BAC clones are bordered; candidate genes are surrounded.
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(a)
329471.fig.001b
(b)